strServerName =""localhost""
strRootPath=""g:\documents"" ''虚拟目录路径
strVRName=""Test"" ''虚拟目录名称
strDefaultDoc=""index.asp"" ''起始文档

Dim objIIS
''MsgBox ""IIS://"" & strServerName & ""/W3SVC/1""

On Error Resume Next
Set objIIS=GetObject(""IIS://"" & strServerName & ""/W3SVC/1"")

If err=-2147024893 Then
MsgBox ""IIS不存在!"" & vbcrlf & ""请验证IIS是否已正确安装!"",vbcritical
Wscript.Quit
ElseIf err<>0 Then
MsgBox ""未知错误!"",vbcritical
Wscript.Quit
End If

On Error GoTo 0

Set objVirtualDir=objIIS.GetObject(""IISWebVirtualDir"",""Root"")
For each VR in objVirtualDir
If VR.Name=strVRName Then
MsgBox ""虚拟目录"" & strVRName & ""已存在!"",vbinformation
Wscript.Quit
End If
Next

On Error Resume Next
Set fs=Wscript.CreateObject(""Scripting.FileSystemObject"")
Set objFolder=fs.GetFolder(strRootPath)

If err=76 Then
MsgBox ""路径"" & strRootPath & ""不存在!"",vbcritical
Wscript.Quit
End If

Set objFolder=nothing
Set fs=nothing
On Error GoTo 0

On Error Resume Next
Set VirDir=objVirtualDir.Create(""IISWebVirtualDir"",strVRName)
VirDir.AccessRead=true
VirDir.Path=strRootPath
VirDir.DefaultDoc=VirDir.DefaultDoc & "","" & strDefaultDoc

VirDir.setInfo

If err<>0 Then
MsgBox ""创建虚拟目录失败!"",vbcritical
Else
MsgBox ""虚拟目录"" & strVRName & ""成功创建在服务器"" & strServerName & ""上!"",vbinformation
End If

代码的关键在于创建虚拟目录，及其中的配置：

Set VirDir=objVirtualDir.Create(""IISWebVirtualDir"",strVRName)
VirDir.AccessRead=true
VirDir.Path=strRootPath
VirDir.DefaultDoc=VirDir.DefaultDoc & "","" & strDefaultDoc

VirDir.setInfo